Saturday will feature three games between the top 25 teams, headlined by the No. 11 Utah plays number 18 UCLA (3:30 p.m. ET on FOX) in a battle of 2-0 teams in Pac-12 Conference play.
Raise your hand if you’ve been waiting TCU and Kansas make the top 25 in week 6? The No. 17 Horned Frogs (1-0 Big 12, 4-0 overall) play against the No. 19 Jayhawks (2-0, 5-0) at 12:30 PM ET on FS1.
The other pair of ranked teams is number 8 Tennessee (1-0, 4-0), playing under No. 25 LDU (2-0, 4-1) in Southeastern Conference interdivision play.
Another noteworthy game among independents Notre Dame game #16 BYU in the Shamrock Series in Las Vegas.
Here’s everything you need to know about the top 25 college football odds for Week 6 – point spread, money line and total over/under (with all college football odds via FOX Bet).
All times are ET
SATURDAY GAMES
No. 4 Michigan @ Indiana (12 p.m., FOX)
Point Spread: Michigan -22.5 (Michigan is favored to win by more than 22.5 points, otherwise Indiana covers)
Cash line: Michigan -1429 favorites to win (bet $10 to win $10.70 total); Indiana +700 underdogs to win (bet $10 to win $80)
Total points over/under: Both teams combined for 59 points
No. 8 Tennessee @ No. 25 LDU (12 p.m., ESPN)
Point Spread: Tennessee is -3 (Tennessee favored to win by more than 3 points, otherwise LSU covers)
Cash line: Tennessee -149 favorites to win (bet $10 to win $16.71 total); LSU is a +115 underdog to win (bet $10 to win $21.50)
Total points over/under: Both teams scored a combined 64 points
No. 17 TCU @ #19 Kansas (12 p.m., FS1)
Point Spread: TCU -7.5 (TCU is favored to win by more than 7.5 points, otherwise Kansas covers)
Cash line: TCU -278 favorites to win (bet $10 to win $13.64 total); Kansas +210 underdogs to win (bet $10 to win $31)
Total points over/under: Both teams combined for 67.5 points
Arkansas @ No. 23 Mississippi State (12 p.m., SEC Network)
Point Spread: Mississippi State -8.5 (Mississippi State is favored to win by more than 8.5 points, otherwise Arkansas covers)
Cash line: Mississippi State -333 favorites to win (bet $10 to win $13); Arkansas is a +240 underdog to win (bet $10 to win $34)
Total points over/under: 62 points scored by both teams combined
South Florida @ No. 24 Cincinnati (2:30 p.m., ESPN+)
Point Spread: Cincinnati -28 (Cincinnati is favored to win by more than 28 points, otherwise Florida South)
Cash line: Cincinnati -3333 favorites to win (bet $10 to win $10.30 total); South Florida +1000 underdogs to win (bet $10 to win $110)
Total points over/under: Both teams combined for 59 points
Chestnut @ No. 2 Georgia (3:30 p.m., CBS)
Point Spread: Georgia -29.5 (Georgia is favored to win by more than 29.5 points, otherwise Auburn covers)
Cash line: Georgia -10,000 favorites to win (bet $10 to win $10.10 total); Auburn +1400 underdogs to win (bet $10 to win $24)
Total points over/under: 50 points scored by both teams combined
Texas Tech @ No. 7 Oklahoma State (3:30 p.m., FS1)
Point Spread: Oklahoma State -9.5 (Oklahoma State is favored to win by more than 9.5 points, otherwise Texas Tech covers)
Cash line: Oklahoma State -333 favorites to win (bet $10 to win $13); Texas Tech is a +240 underdog to win (bet $10 to win $34)
Total points over/under: Both teams combined for 67.5 points
No. 11 Utah @ No. 18 UCLA (3:30 p.m., FOX)
Point Spread: Utah -4 (Utah is favored to win by more than 4 points, otherwise UCLA covers)
Cash line: Utah -182 favorites to win (bet $10 to win $15.49 total); UCLA is a +140 underdog to win (bet $10 to win $24)
Total points over/under: Both teams combined for 64.5 points
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No. 3 Ohio State @ State of Michigan (4 p.m., ABC)
Point Spread: Ohio State -25.5 (Ohio State is favored to win by more than 25.5 points, otherwise Michigan State)
Cash line: Ohio State -2000 favorites to win (bet $10 to win $10.50 total); Michigan State is a +800 underdog to win (bet $10 to win $90)
Total points over/under: 63 points scored by both teams combined
No. 9 Ole miss @ Vanderbilt (4 p.m., SEC Network)
Point Spread: Ole Miss -18.5 (Ole Miss favored by more than 18.5 points, otherwise Vanderbilt covers)
Cash line: Ole Miss -1000 favorites to win (bet $10 to win $11); Vanderbilt is a +550 underdog to win (bet $10 to win $65)
Total points over/under: Both teams combined for 59.5 points
No. 21 Washington @ State of Arizona (4 p.m., Pac-12 Network)
Point Spread: Washington -14 (Washington is favored to win by more than 14 points, otherwise covering Arizona State)
Cash line: Washington -556 favorites to win (bet $10 to win $11.80 total); Arizona State +375 underdogs to win (bet $10 to win $47.50)
Total points over/under: Both teams combined for 58.5 points
No. 5 Clemson @ Boston College (7:30 p.m., ABC)
Point Spread: Clemson -20.5 (Clemson is favored to win by more than 20.5 points, otherwise Boston College covers)
Cash line: Clemson -1429 favorites to win (bet $10 to win $10.70 total); Boston College is a +700 underdog to win (bet $10 to win $80)
Total points over/under: 50 points scored by both teams combined
Washington State @ No. 6 USC (7:30 p.m., FOX)
Point Spread: USC -13.5 (USC is favored to win by more than 13.5 points, otherwise Washington State)
Cash line: USC -500 favorites to win (bet $10 to win $12); Washington State +300 underdogs to win (bet $10 to win $40)
Total points over/under: Both teams scored a combined 66 points
South Carolina @ No. 13 Kentucky (7:30 p.m., SEC Network)
Point Spread: Kentucky -11 (Kentucky is favored to win by more than 11 points, otherwise South Carolina covers)
Cash line: Kentucky is a 500 favorite to win (bet $10 to win $12); South Carolina +300 underdogs to win (bet $10 to win $40)
Total points over/under: Both teams combined for 49.5 points
Army @ No. 15 Wake Forest (7:30 p.m., ESPN3)
Point Spread: Wake Forest -17 (Wake Forest is favored to win by more than 17 points, otherwise Army covers)
Cash line: Wake Forest -714 favorites to win (bet $10 to win $11.43 total); An army of +450 underdogs to victory (bet $10 to win $55)
Total points over/under: Both teams combined for 67.5 points
No. 16 BYU against Notre Dame @ Las Vegas (7:30 p.m., NBC/Peacock)
Point Spread: Notre Dame -3.5 (Notre Dame is favored by more than 3.5 points, otherwise BYU covers)
Cash line: Notre Dame -189 favorites to win (bet $10 to win $15.29 total); BYU is a +145 underdog to win (bet $10 to win $24.50)
Total points over/under: 52 points scored by both teams combined
No. 20 Kansas State @ Iowa State (7:30 p.m., ESPNU)
Point Spread: Kansas State -2 (Kansas State is favored to win by more than 2 points, otherwise Iowa State)
Cash line: Kansas is a 133 favorite to win (bet $10 to win $17.52 total); Iowa State +105 underdogs to win (bet $10 to win $20.50)
Total points over/under: Both teams combined for 45.5 points
Texas A&M @ No. 1 Alabama (8 p.m., CBS)
Point Spread: Alabama -24 (Alabama is favored to win by more than 24 points, otherwise Texas A&M covers)
Cash line: Alabama -2500 favorites to win (bet $10 to win $10.40 total); Texas A&M is a +900 underdog to win (bet $10 to win $100)
Total points over/under: Both teams scored a combined 51 points
No. 12 Oregon @ Arizona (20:00, TV – TBD)
Point Spread: Oregon -13.5 (Oregon is favored to win by more than 13.5 points, otherwise covers Arizona)
Cash line: Oregon is a 500 favorite to win (bet $10 to win $12); Arizona +300 underdogs to win (bet $10 to win $40)
Total points over/under: 70 points scored by both teams combined
State of Florida @ No. 14 North Carolina State (8 p.m., ACC Network)
Point Spread: North Carolina State -3 (North Carolina State wins by more than 3 points, otherwise covers Florida State)
Cash line: North Carolina State -167 favorites to win (bet $10 to win $15.99 total); Florida State is a +130 underdog to win (bet $10 to win $23)
Total points over/under: 52 points scored by both teams combined
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